| 1 | Mia Manganello (Senior) | USA | 1:17.32 | | - |
| 2 | Sarah Warren (Senior) | USA | 1:17.65 | | +0.330 |
| 3 | Sofia Prosvirnova (Senior) | DEN | 1:18.23 | NR | +0.910 |
| 4 | McKenzie Browne (Senior) | USA | 1:18.90 | | +1.580 |
| 5 | Anna Quinn (Senior) | USA | 1:21.13 | | +3.810 |
| 6 | Libby Williams (A2) | USA | 1:23.44 | | +6.120 |
| 7 | Isabela Vargas Rodriguez (B2) | COL | 1:23.81 | | +6.490 |
| 8 | Lindsey Woodbury (Neo) | USA | 1:24.56 | | +7.240 |
| 9 | Melissa Dahlmann (M40) | USA | 1:24.99 | | +7.670 |
| 10 | Rebecca Simmons (M35) | USA | 1:28.59 | | +11.270 |
| 11 | Laura Michelle Rodriguez (A1) | COL | 1:29.17 | | +11.850 |
| 12 | Karen Lizeth Siatama Valencia (A1) | COL | 1:31.01 | | +13.690 |
| 13 | Emma de Bock (C2) | USA | 1:31.54 | | +14.220 |
| 14 | Clare Jeong (Senior) | USA | 1:32.06 | SB | +14.740 |
| 15 | Leah Choi (B1) | USA | 1:33.20 | | +15.880 |
| 16 | Rz Love (C2) | USA | 1:33.92 | PB | +16.600 |
| 17 | Mariana Acero Pineda (C1) | COL | 1:37.57 | PB | +20.250 |
| 18 | Audrey Han (B1) | USA | 1:38.49 | | +21.170 |
| 19 | Kaitlyn Lee (C2) | USA | 1:38.71 | | +21.390 |
| 20 | Juliette Song (D2) | USA | 1:43.25 | SB | +25.930 |
| 21 | Elisha Lee (D2) | USA | 1:44.79 | SB | +27.470 |
| 22 | Kaylin La (D2) | USA | 1:48.41 | SB | +31.090 |
| 23 | Baily Luck (Senior) | USA | 1:48.52 | SB | +31.200 |
| 24 | Allison La (D2) | USA | 1:48.55 | SB | +31.230 |
| 25 | Scarelette Gramlich Thatcher (D2) | USA | 1:49.85 | SB | +32.530 |
| 26 | Atira Meacham (E1) | USA | 2:09.63 | PB | +52.310 |
| DNF | Brittany Bowe (Senior) | USA | DNF | | - |
| DQ | Selena Su (B1) | USA | DQ | | - |